domenica 30 ottobre 2016

martedì 25 ottobre 2016

How Our Other Genome Controls Our Epi-Genome - Trends in Microbiology


The Vitruvian Man, marking pen and Photoshop. 
Illustration for:"How Our Other Genome Controls Our Epi-Genome" in Trends in Microbiology, October 2016, Volume 24, Issue 10, p. 777-787



"Eukaryotes and prokaryotes produce extracellular nanovescicles that contain RNAs and other molecules that they exploit to communicate. Recently, inter-kingdom crosstalk was demonstrated between humans and bacteria through fecal microRNAs. We suggest here how bacteria interact with humans via RNAs within membrane vesicles to alter our epigenome, thus filling the gap and closing the circle. At the same time, there are indications that there could be a wider inter-kingdom communication network that might encompass all known kingdoms. Now that the connection with our other genome has been established, we also should begin to explore the ‘social’ network that we have around us." Antonella Celluzzi, Andrea Masotti (2016): "How Our Other Genome Controls Our Epi-Genome", Trends in Microbiology, Cell Press.